Corporate Information



Keelung Hong
Founder, Chairman & CEO

Dr. Hong founded our company in 1997 and has served as Chairman of the board of directors since January 2002 and Chief Executive Officer since January 2005. Prior being our CEO, Dr. Hong was our Science and Technology Adviser from 1997 to 2004. Dr. Hong co-founded Hermes Biosciences, Inc. and served as its Chief Scientific Officer from 1999 to 2005. Before venturing into the world of drug development, Dr. Hong served as Research Scientist for the California Pacific Medical Center Research Institute from 1998 to 2002. Prior to that, Dr. Hong was a Scientist at the Liposome Research Laboratory at the Cancer Research Institute of the University of California, San Francisco from 1979 to 1998. Dr. Hong has served as a consultant to various biopharmaceutical companies over the years.


Dr. Hong received a Ph.D. in Chemistry from the University of California, Berkeley, an M.S. in Chemistry from the University of Texas at El Paso, and a B.S. in Chemistry from Taiwan Cheng Kung University.

George Yeh

Mr. Yeh has served as the President of TLC since 2002. Prior to joining TLC, Mr. Yeh was Vice President of AsiaWired Group, Inc., a venture advisory company, from 1999 to 2002. Before AsiaWired Group, Mr. Yeh was an associate at General Bank, a U.S.-based commercial bank. Mr. Yeh also served as the Chief Financial Officer of Hermes Biosciences, Inc. from 2002 to 2005, where he first started working alongside Dr. Keelung Hong.


Mr. Yeh received a Master of Architecture and an M.B.A. from the University of Michigan. He received a B.A. in Architecture from the University of California, Berkeley.

George Spencer-Green
Chief Medical Officer

Dr. Spencer-Green brings with him experience as the prior Vice President and clinical head of Pfizer’s biosimilars development program, where he led the team that designed and initiated clinical development plans from Phase 1 to Phase 3 for five assets. Prior to Pfizer, he served as the Senior Medical Director at Vertex Pharmaceuticals, where he led the design and execution of clinical development programs in rheumatoid arthritis and cystic fibrosis. Prior to Vertex, he was the Global Medical Director at Abbott Laboratories, and was the clinical lead for the rheumatoid arthritis registration and long-term extension programs for Humira. At Immunex Corporation, where he worked prior to Abbott Laboratories, he was Franchise Medical Director for Enbrel, the first targeted biologic treatment approved for the treatment of rheumatoid arthritis. 

Dr. Spencer-Green received his BA from Oberlin College, his MD from Columbia University College of Physicians and Surgeons, and his MS in Clinical Evaluative Science from Dartmouth College. 

Nicole Lin
Vice President

Ms. Lin has served as our Vice President in Finance and Administration since 2014. Prior to that, Ms. Lin served as our Director and controller from 2005 to 2013. Before joining us, Ms. Lin served as Accounting Supervisor at MaLab Inc., a computer component distributor, in 2004. Before that, Ms. Lin served as Accounting Manager at NextGen Communications, a high-technology start up, from 2001 to 2004. Ms. Lin obtained finance and banking experience when she served as Commercial Loan Officer within the High Tech/Venture Division of General Bank, a US-based commercial bank, from 1998 to 2001. Ms. Lin served as Security Underwriter at Taiwan Securities Co., Ltd., a securities firm, from 1995 to 1998, and at Rick Chen CPA Firm from 1990 to 1995. 

Ms. Lin received her MBA from the University of California, Riverside and her Bachelors in International Trade from Soochow University in Taipei, Taiwan. She is a US Certified Public Accountant.

Yunlong Tseng
Vice President, Research & Development

Dr. Tseng is the co-inventor of TLC's NanoX™ technology and has served as our Vice President of Research and Development since January 2014. Prior to holding that position, Dr. Tseng was our Director of Research and Development from 2002 to December 2013. Prior to joining TLC, Dr. Tseng conducted his postdoctoral research at the Department of Oncology at National Taiwan University Hospital. 

Dr. Tseng received a Ph.D. in Biochemistry from National Taiwan University, College of Medicine, and a BS in Chemistry from Tamkang University, Taiwan.

Wenji Chen
Ph.D., M.B.A.
Vice President, Corporate Development

Dr. Chen has served as our Vice President of Corporate Development since October 2016. Before joining TLC, Dr. Chen was the Vice President of Industrial Promotion at the Development Center of Biotechnology in Taiwan from January 2016 to August 2016. Prior to that, Dr. Chen was Senior Director of Worldwide Business Development at GlaxoSmithKline China R&D Co., Ltd. in Shanghai, China from 2010 to December 2015. Dr. Chen served as Director of Worldwide Business Development at GlaxoSmithKline LLC in the Research Triangle Park facility in North Carolina from 2006 to 2010 and Business Development Director at Norak Biosciences Inc., a biotechnology firm, from 2002 to 2005. From 1992 to 2002, Dr. Chen was a principle investigator in the Research and Development Division of GlaxoSmithKline in the Research Triangle Park facility in North Carolina.

Dr. Chen received a Ph.D. from the University of Texas Southwestern Medical Center, an M.B.A. from the University of North Carolina, Chapel Hill, and a B.S. from National Taiwan University, Taipei, Taiwan.

Hung Wei Chih
Vice President - Manufacturing Development Division

Dr. Chih joined TLC in July 2018 as the Vice President of Manufacturing Development. Dr. Chih has over 15 year experience in the biotech industry. He has ample experience from his tenure at Genentech/Roche in South San Francisco across departments including product quality, early and late stage pharmaceutical development, and technical regulatory. Dr. Chih's leadership and operation excellence has won him a Great Manager Award, a PR&D Process Improvement Award, and three Key Contributor Awards while at Genentech/Roche. Prior to joining TLC, Dr. Chih served as the Director of IMP Product Quality at Genentech/Roche. Before Genentech/Roche, Dr. Chih was a Scientist at ImmunoGen and Investigator at ArQule, both in Massachusetts.


Dr. Chih received his PhD in Chemistry from the University of Michigan, where he received an Outstanding Graduate Research Award, and his BS in Chemistry from the National Sun Yat-Sen University.

Sheue Fang Shih
Senior Director, Product Development

Dr. Shih joined TLC in 2002. Dr. Shih has more than 15 years of experience in drug development. Her research focuses on the development of protein drug delivery, antibody discovery and targeted drug delivery with immunoliposomes. In her role as Manager/Project Leader, Dr. Shih led various research and development programs in areas of retinal diseases and arthritis and received IND approvals from the U.S. FDA as well as Taiwan FDA. Her current role specializes in drug development, product development strategy, non-clinical and clinical operations as well as planning. Dr. Shih has authored a number of scientific publications and is the inventor of a novel anti-VEGF antibody and several drug delivery patents.

Dr. Shih received her Ph.D. and completed postdoctoral research from the Department of Biochemistry at National Taiwan University’s College of Medicine.

Carl Brown
Director, Product Development

Dr. Brown has over 13 years’ experience in clinical development in the biotechnology and pharmaceutical industry. Prior to joining TLC in 2017, Dr. Brown was Senior Director of Medical Research at TWi Biotechnology, where he oversaw clinical development activities for new drugs in multiple therapeutic areas as well as patient trials for 505(b)(2) and ANDA projects. Dr. Brown was also previously in Clinical Development at Amylin Pharmaceuticals in San Diego, California, where he ultimately made Senior Clinical Investigator and was involved in multiple projects in diabetes and obesity and contributing to IND, NDA, and sNDA submissions. Dr. Brown has experience in clinical and regulatory strategy, protocol development, trial oversight, data analysis, medical writing, and data communications.

Dr. Brown received his Ph.D. in Molecular and Cellular Biology from Baylor College of Medicine in Houston, Texas, and performed postdoctoral research at the Salk Institute for Biological Studies in La Jolla, California.

Cynthia Lin
Director of Clinical Operations, Clinical Development, Product Development

Ms. Lin possesses more than 19 years of experience in the pharmaceutical industry, having undertaken roles in manufacturing plant quality assurance, marketing, research laboratory, medical/regulatory administration, clinical research, project management, people/line management, and business/therapeutic strategy. With the last 14 years in clinical research handling both global/multi-national studies (phase I, II, III and IV) across Asia and Europe, Ms. Lin has gained significant experience in oncology, cardiovascular diseases, neurology, respiratory diseases, endocrine/metabolism, and infectious disease. Ms. Lin’s experience spanned the full duration of clinical projects, including overall project strategy and budgeting, project set-up, protocol and CTA finalization, feasibility, project start-up to close-out, vendor management, regulatory inspection, and coordination of back-end functions (Bios/DM/Medical/PhV/central Lab/vendors). Cynthia’s diverse experience has helped develop abilities in optimal communication with external and internal customers as well as strong project and time management skills.


Ms. Lin holds a master’s degree in microbiology from National Taiwan University.

Terry Tai
Director, Portfolio & Strategy

Dr. Tai has more than 10 years of experience in regulatory science as a medical reviewer and consultant at the Center for Drug Evaluation (CDE), Taiwan. In the role of Senior Medical Reviewer/IND Review Team Leader, Dr. Tai has reviewed more than 200 IND cases and was instrumental in developing multiple TFDA draft guidance documents for new drug development. As the Consultation Center’s Director, he provided scientific and strategic leadership to a multidisciplinary (CMC/PT/PK/Clinical/Stat.) regulatory consultation team consisting of senior reviewers and project managers and offered integrated consultation services to new drug development pipelines from pharmaceutical industries/research institutes. Dr. Tai was designated as the principal investigator/co-PI in multiple government-sponsored programs, such as the TFDA-sponsored “Cross-strait Cooperation Agreement on Medicine and Public Health Affairs”, where he led the collaboration between the TFDA/CDE and CFDA-CDE to execute the Cross-strait Collaborative Platform on Technical Review of Drug and provided Mainland China Regulatory Consultation Service to domestic pharmaceutical companies interested in submitting a CTA/NDA/ANDA to the CFDA.

Dr. Tai received his M.D. from Taipei Medical University and practiced at Mackay Memorial Hospital and Chung-Shan Medical University Hospital. He has been a board-certified physician of Physical Medicine & Rehabilitation since 2004.

Bella Kuo
Director, Quality Assurance

Ms. Kuo has more than 19 years of experience in the pharmaceutical industry. Prior to joining TLC, Ms. Kuo was the associate head of project management, responsible for project/grant management at PharmaEngine Inc. Prior to PharmaEngine, Ms. Kuo was Project Manager at TTY Biopharm Co., Ltd., where she established the R&D management process and was responsible for the management of SBIR’s small chemical compound projects and liposome formulation grant projects. At TTY Biopharm, Ms. Kuo successfully assisted the company in winning the Industrial Technology Development Award of Ministry of Economic Affairs. Before TTY Biopharm, Ms. Kuo assisted government-sponsored projects such as pharmaceutical facility audits, cGMP guideline drafting and training programs at the Pharmaceutical Industry Technology Development Center and Taiwan Parenteral Drug Association.

Ms. Kuo holds a bachelor’s degree from the Department of Animal Science and Technology, National Taiwan University. She also holds a graduate certificate in Engineering and Technology Management from George Washington University.

Wayne Liao
Director of Operations, TLC United States

Dr. Liao has more than 17 years of experience in biotech and pharmaceutical industries. Prior to joining TLC, he held R&D and product development positions at Deltagen, PhalanxBio, and Verinata (now Illumina). Dr. Liao joined TLC in 2007 and was a part of various drug development programs at IND or ANDA stages. Dr. Liao is currently managing TLC’s US subsidiary in South San Francisco focusing on early development of pharmaceutical products.

Dr. Liao received his PhD in Pharmaceutical Science at USC and conducted research at UCSF Department of Biochemistry as an American Heart Association Postdoctoral Fellow.